Welcome to the ePoster Viewing Panel of AICOG 2025

Introduction: Idiopathic thrombocytopenic purpura (ITP) involves platelet destruction by IgG antibodies, causing thrombocytopenia and bleeding, hence complicating pregnancy. Management includes corticosteroids, IVIG, thrombopoietin agonists, with close monitoring to ensure fetomaternal safety. Aims and Objectives: 1. Explore impacts on fetomaternal outcome including risks of bleeding, fetal thrombocytopenia, preterm birth, still birth. 2. Evaluate and asses management strategies like corticosteroids, IVIG and thrombopoietin receptor agonists. 3. Highlight a multidisciplinary approach and individualized care for safe delivery outcomes. Materials and Methods : Case: 24-year-old primigravida with chronic ITP previously on Eltrombopag 25 mg OD for 9 months before pregnancy. Treatment during pregnancy: 1. Wysolone i.e. prednisolone started at 40 mg BD, dose adjusted after monitoring platelet counts. 2. Injection Methylprednisolone administered (at counts below 15,000/?L). 3. Azathioprine 50 mg OD. Clinical Course: 1. Regular platelet count monitoring. 2. Preterm baby delivered vaginally without complications/ PPH. Post-delivery treatment: IVIG (2 g/kg over 5 days), Wysolone 60 mg OD and Eltrombopag (25 mg OD). Result: Maternal Outcome: The case resulted in a successful maternal outcome. The mother?s platelet counts were managed effectively with Wysolone and azathioprine. Adverse effects like Exogenous Cushings syndrome was closely monitored and managed conservatively. Delivery was uneventful without any complications/ PPH. Post-delivery the platelet counts were stabilized with IVIG and eltrombopag. Neonatal Outcome: The baby was delivered preterm and had fetal thrombocytopenia which required conservative management. The mother was discharged with a healthy baby. Conclusion: This case study highlights the successful management of chronic ITP during pregnancy, demonstrating that effective monitoring and individualized treatment can lead to favorable outcomes for both mother and baby. Fetal thrombocytopenia though encountered was managed conservatively and mother was discharged with a healthy baby, giving a positive fetomaternal outcome. This underscores the importance of a multidisciplinary approach in managing chronic ITP in pregnancy.