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Title: A RARE CASE OF ENDOMETRIAL CARCINOMA: A CASE REPORT
e-poster Number: EP 224
Category: Gynaecologic Oncology
Author Name: Dr. Soumyashree V Halhalli
Institute: Mahadevappa Rampure Medical College , kalaburagi , Karnataka
Co-Author Name:
Abstract :
INTRODUCTION Endometrial carcinoma is the 3rd highest gynaecological cancer in India, mainly with postmenopausal bleeding. Diagnosed by biopsy, hysterectomy being primary treatment followed by adjuvant therapy depending on staging. AIM AND OBJECTIVES To study a case of a 51-year-old nulligravida female patient diagnosed with endometrial carcinoma. MATERIAL AND METHODS In this study the patient had complaints of PV bleeding for 3 months. After endometrial biopsy, histopathology showed endometrial hyperplasia with atypia. On examination uterus normal size & retroverted with B/L fornices free, non-tender. Patient underwent type I extrafascial hysterectomy with pelvic sentinel lymph node biopsy. HPR showed: Endometroid carcinoma with squamous differentiation, histological grade 3 with myometrial invasion of >50%, no lymphatic or vascular invasion or distant metastasis, with FIGO Stage IIC. Postoperatively patient underwent adjuvant therapy. RESULTS In view of diagnostic suspicion, clinical data and biopsy findings, patient underwent type I extrafascial hysterectomy with pelvic sentinel lymph node biopsy, under spinal with epidural anaesthesia and an irregular tumor lesion was identified. The histopathology report showed: Endometroid carcinoma with squamous differentiation, histological Grade 3 with myometrial invasion of >50%(1.5cm) and no lymphatic or vascular invasion or distant metastasis, with FIGO Stage IIC. Adjuvant therapy was indicated postoperatively. CONCLUSION Endometrial carcinoma is one of the most prevalent gynaecological cancers, mainly among postmenopausal women. Assessment is done by pelvic examination, dilatation and curettage, endometrial biopsy, transvaginal ultrasound, MRI. Molecular classification has paved way for targeted chemotherapy. The current protocol for surgical management includes peritoneal cytology, hysterectomy with bilateral salpingo-oophorectomy and surgical staging. Clinical trials have benefited in adjuvant therapy in advanced and recurrent disease.
