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Title: THROMBOCYTOPENIA IN THIRD TRIMESTER OF PREGNANCY

e-poster Number: EP 378

Category: Maternal and Fetal Health
Author Name: Dr. Rashi Jain
Institute: GMC KOTA
Co-Author Name:
Abstract :
INTRODUCTION In pregnancy, thrombocytopenia (platelet count <1.5 Lacs/L) is the 2nd most common haematological condition (Prevalence 7-11%). Gestational thrombocytopenia is the most common cause followed by HDP. AIM OF THE STUDY- To study the etiology & fetomaternal outcome in patients presenting with thrombocytopenia in third trimester of pregnancy. MATERIALS AND METHODS- We did a retrospective descriptive study to get 100 cases of thrombocytopenia in third trimester of pregnancy of women who delivered their babies in JK Lone Kota & analysed their health records to understand the etiology & effect on fetomaternal outcome. RESULTS- We studied 860 health records to collect 100 cases from Sept 2024 to Nov 2024. Prevalence came out to be 8.6%. Mostly, the patients were primigravida & at term gestation. 45% patients had platelet count less than 1 lac/uL. 52% patients had no identifiable risk factor or etiology & among them, 42% patients had platelet count between 1-1.5 lac/uL. 28% patients had history of fever (dengue, scrub typhus, malaria etc) 22% patients suffered from HDP, 7% patients had Abruption placenta with HDP. 5% patients had IUFD, among them, 4 had HDP. 78 patients had anaemia (Hb < 11gm/dl) ,9 patients had severe anaemia (Hb < 7 gm/dl) & out of 9, six had fever. Out of 95 alive babies, 44 needed NICU care. 59% patients developed complications like bleeding tendency, PPH, AKI, Sepsis etc. CONCLUSION- 1. Most common cause of thrombocytopenia in pregnancy is gestational thrombocytopenia followed by HDP. 2. Incidence of thrombocytopenia increased till term gestation likely due to hemodilution or more platelet activation or destruction. 3. History of fever is associated with worsening of thrombocytopenia and maternal complications. 4. Neonatal outcome is not influenced by thrombocytopenia as sole factor.