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ACUTE TRANSVERSE MYELITIS IN PREGNANCY By, Dr. KAKARA MAITHRI , Dr. ANNAPOORNA INTRODUCTION: Transverse myelitis is a rare neurological disorder that damages the myelin covering the spinal cord, usually symmetrical in nature. This focal spinal cord inflammation can cause sensory problems, muscle weakness, paralysis, pain, autonomic dysfunction, or bladder and bowel dysfunction. Management of pregnancy in such patients is a big challenge. AIM AND OBJECTIVE: To present a case of Acute Transverse myelitis in pregnancy. METHODS: A prospective analysis of a case seen and presented at a tertiary care centre was performed. CASE REPORT: oA 23-year-old primigravida with 32weeks 6days POG with c/o bilateral lower limb weakness since 4days. She has a sudden onset of weakness which is progressive in nature. She had a c/o involuntary micturition and defecation since 2days. oShe had a h/o decreased vision in right eye in 2017 followed by complete loss of vision of the same eye in 2019. She had similar complaints of lower limb weakness in 2019. oMRI shows Multiple focal T2WI/ flair hyperintensities in bilateral frontal and parietal lobes, subcortical, periventricular and deep white matter- Abnormal spinal cord signal intensities extending from D2-D6 vertebral body levels. Bilateral optic atrophy. All the findings are suggestive of Demyelinating disease ? possibility of NMOSD (Neuromyelitis optica spectrum disorder) with Acute transverse myelitis. oHer recent growth scan corresponds to 30 weeks parameters. RESULTS: Results will be disclosed at the time of presentation. CONCLUSION: Neuro-Myelitis Optica is a rare demyelinating entity which is progressive in nature. Pregnancy further complicates the care of these women especially in the setting of transverse myelitis. A multi-disciplinary team approach is needed to better the outcomes of the mother and child. Key words: Demyelinating disease, pregnancy