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Title: ALL IS WELL IN INFERTILITY CHALLENGES ENDING WELL WITH EOS DIAGNOSIS
e-poster Number: EP 177
Category: Infertility Diagnosis and Treatment
Author Name: Dr. Vandana R Saravade
Institute: TNMC BYLNair Ch Nair Hospital
Co-Author Name:
Abstract :
Osseous metaplasia of the endometrium is a rare condition characterized by the presence of mature or immature bone tissue within the endometrial cavity. It is often reported in reproductive age group women and associated with secondary infertility and recurrent miscarriage, posing significant clinical and diagnostic challenges. The exact pathogenesis remains uncertain, with proposed mechanisms including chronic endometrial inflammation, retained embryonic tissue, and abnormal differentiation of mesenchymal stem cells in the endometrial cavity.
We report one such case with brief review of literature in ? 29? years old woman presenting with complain of? irregular menses and? diagnostic imaging USG and HSG suggestive of intrauterine calcifications. Hysteroscopic removal done. Histopathological examination confirmed osseous metaplasia, revealing mature bone fragments in the endometrial stroma. This presentation aims to increase awareness of this rare entity, aiding clinicians in recognizing and managing osseous metaplasia, ultimately improving patient outcomes.
conclusion
Endometrial ossification is a rare but treatable cause of infertility in which intrauterine bone prevents normal conception. Chronic endometritis evokes metaplastic changes in the pluripotent endometrial stromal cells into osteoblastic cells that lay down bone. Surgical pathologists should be aware of the condition to avoid making erroneous diagnosis of malignant mixed m?llerian tumor of endometrium. Complete removal of the bony spicules from the endometrial cavity by hysteroscopy? regains the fertility in pregnancy desirous women.
